Detalhe da pesquisa
1.
POLIE suppresses telomerase-mediated telomere G-strand extension and helps ensure proper telomere C-strand synthesis in trypanosomes.
Nucleic Acids Res
; 50(4): 2036-2050, 2022 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35061898
2.
TbTRF suppresses the TERRA level and regulates the cell cycle-dependent TERRA foci number with a TERRA binding activity in its C-terminal Myb domain.
Nucleic Acids Res
; 49(10): 5637-5653, 2021 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34048580
3.
Synthesis and biological evaluation of imidamide analogs as selective anti-trypanosomal agents.
Bioorg Med Chem
; 61: 116740, 2022 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35396128
4.
The RRM-mediated RNA binding activity in T. brucei RAP1 is essential for VSG monoallelic expression.
Nat Commun
; 14(1): 1576, 2023 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36949076
5.
Identification of Prazosin as a Potential Flagellum Attachment Zone 1(FAZ1) Inhibitor for the Treatment of Human African Trypanosomiasis.
ACS Infect Dis
; 8(8): 1711-1726, 2022 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35894227
6.
TbRAP1 has an unusual duplex DNA binding activity required for its telomere localization and VSG silencing.
Sci Adv
; 6(38)2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32948591
7.
Trypanosoma brucei RAP1 Has Essential Functional Domains That Are Required for Different Protein Interactions.
mSphere
; 5(1)2020 02 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32102938